Health and Ayurveda

Tuesday, May 29, 2007

MUSCULAR DYSTROPHY DISEASES

The weakness of muscles (myopathies) is the diseases interfere with chemical reactions involved in drawing bio-energy (Prana shakti) from food. Normal, fuel molecules derived from food must be broken down further inside each cell before they can be used by the cells; mitochondria to make the energy molecule ATP. The mitochondria inside each cell could be called the cells; “energies.” The metabolic muscle diseases are caused by problems in the way certain fuel molecules are processed before they enter the mitochondria, or by the inability to get fuel molecules in to mitochondria. Muscle required a lot of energy in the form of ATP to work properly. When energy levels become too low, muscle weakness and exercise intolerance with muscle pain or cramps may occur.
In a few metabolic muscle disorders, symptoms aren’t caused so much by a lack of energy, but rather by unused fuel molecules that build up inside muscle cells. This buildup may damage the cells, leading to chronic weakness. Metabolic muscle diseases that have their onset in infancy tend to be the most severe, and some forms are fatal. Those that begin in childhood or adulthood tend to be less severe, and changes in diet and lifestyle can help most people with the milder forms adjust.

What causes muscle weakness?
Most muscle weakness is caused by defects in the enzymes (Agnis) that control chemical reactions used to breakdown food. Enzyme defects are caused by flaws in the genes that govern production of the enzymes. A gene is a “recipe” or set of instructions for making a protein, such as an enzyme. A defect in the gene may cause the protein to be made incorrectly or not al all, leading to deficiency in the amount of that enzyme. Genes are passed from parents to children. Therefore genetic defects can be inherited.
In normal metabolism, food provides fuel that’s processed inside the cells, producing energy (ATP) for muscles contraction and other cellular functions. In metabolic myopathies, missing enzymes prevent motochondria from properly processing fuel, and no energy is produced for muscle function.
Muscular dystrophy refers to a group of genetic diseases characterized by progressive weakness and degeneration of the skeletal or voluntary muscles which control body movement. The muscles of the heart and some other involuntary muscles are also affected in some forms of muscular dystrophy, and a few forms involve other organs as well. The muscular dystrophies include many inherited disorders such as: Becker’s, Duchenne, Facioscapulo-humeral, Limb-girdle, Emery-Dreifuss, and Myotonic and myotonia congenita.

Most common neuro muscular disease among children
Most children are affected by muscular dystrophies, inflammation of muscles, cerebral palsy, motor problems related to injuries at the time of birth or thereafter, and also birth-related injuries to the arms and legs – mostly to the nerves in the arms.
The most common diagnosis would be spasticity in children, muscular dystrophy and different kinds of delays such as not walking, crawling and so on. Other less common problems are spinal muscular atrophy, neuropathies and so on.
Duchenne muscular dystrophy is the most common form affecting children, and myotonic muscular dystrophy is the most common form affecting adults. Muscular dystrophy can affect people of all ages. Although some forms first become apparent in infancy or childhood, other may not appear until middle age or later.
These diseases are distinguished from each other by the type of inheritance (sex-linked, dominant gene, recessive gene), the age when symptoms appear, and the types of symptoms that develop. Because these are inherited disorders, risks include a family history of muscular disease.

Symptoms of muscular dystrophy
Weakness is primary symptom
  • Progressive frequent falls
  • Delayed development of muscle motor skills
  • Difficulty in walking (delayed walking)
  • Difficulty using one or more muscle groups (the specific muscles affected depends on the type of dystrophy)
  • Poor muscle tone and curved spine

Muscular dystrophy is diagnosed by serum CPK (an enzyme found in muscle) and EMG (electromyography). An ECG is also done to monitor changes in cardiac status.

This disease may also alter the results of the following tests:

  • Myoglobin in urine / serum
  • LDH (lactate dehydorgenase)
  • Creatinine
  • AST (aspartate aminotrasferase)

What are the complications?

  • Joint contractures, deformities and scoliosis
  • Permanent progressive disability
  • Decreased functional ability to care for self
  • Mental impairment and depressive manifestations
  • Cardiomyopathy, respiratory failure and death

What is the prevention?
Women may be asymptomatic but still be carrier of gene for the disorder. Duchenne muscular dystrophy can be detected with about 95% accuracy by genetic studies performed during pregnancy

New treatment options
There is a big push to find a cure or at least modify the problems in different ways. There are newer treatment options.
Panchkarma therapies, specially developed molecules (mamsagni rasayan) and yogic techniques may be effective in the long term management of muscular weakness. It may help people to maintain muscle strength and function. In addition, some people with metabolic disorders have benefited from strict ayurvedic dietary changes. There is evidence that those with carbohydrate-processing problems may be helped by a natural high protein diet, while those with difficulty processing fats may do well on a natural diet high in carbohydrates and low in fats.
Ayurvedic herbs which safe guard the function of liver can be very effective in reversing heart failure in the patient of myopathies. Orthopedic appliances such as braces and wheelchairs can improve mobility and self care abilities. In some cases, surgery on spine or lower extremities may help improve function and slow deterioration.
Ayurveda considers this condition as mamsa – vata – kshaya (MVK) related to beeja dosha and impairments of mamsagni (muscle enzyme). It involves deranged vata and subsequent degeneration of muscles and structures related to it. Ayurvedic treatment might slow or stop the progressive of muscle degeneration. A combined strategy of age old Til Mash Pinda sweda (TMP), pizhichil, anuvasana vasti, mamsagni rasayana and yogic support is effective in the long term management of muscular weakness.

Mamsagni rasayana
The mamsagni G is gurvel, guggul and gold (G3) based new ayurvedic formula developed by Ayurveda Acharya Mukesh Dev Jain in 1998 for his care through research project on neuromuscular diseases. The active ingredients are bio-enhanced and standardized marich, triphala, gurvel, guggul, kuchla, parad and gold bhasma. This new compound molecule regulates muscular metabolism and useful as a safe ayurvedic medicine for the management of muscular dystrophies.
The marich promoted mamsagni (muscle enzyme system) triphala guggulu is well known srotorodhahara (correct membrane defect) and regulated fat metabolism. Kuchla boost the neuromuscular tone while the gold bhasma retards the process of muscular degeneration. Gurvel also called amrita (nectar) is best immunity modulating (rasayana) drug. The combined effect is neuro-muscular vata-pitta-kapha balancing which is evident by promising clinical results such as weight loss, decrease in blood CPK level, decrease in walking difficulty, increase in neuro-muscular tone

The practical therapeutic benefits of weight reduction are not only obvious but potentially greater i.e. improved muscle power/ weight ratio.

Dose: the therapeutic oral dose is 20 mg/kg body weight administered in two divided doses. The medicine can be given preferably before meals with honey or with dasmula ghrita.

Dr. Mukesh D Jain MD
Global ayurveda (Dec-Jan 2007)

18 Comments:

  • i m vijay tamrakar from bhopal(M.P.)Suffering from muscular dystrophy i want to know latest treatment of this disease & progress about it.Please inform me . thanks

    By Blogger Unknown, at 8:44 AM  

  • hiii i am vianni i am from chennai my sister is affecting from muscular dystrophy for 8 years there is any treatment for her pls tel

    By Blogger Unknown, at 1:49 AM  

  • Good Presentation and informative, I found some other combinations from http://www.lovenaturalremedies.com/Divya-Yog-Mandir-Trust-Swami-Ramdev/Herbal-/-Ayurvedic-Packages-For-Diseases/Muscular-Distrophy-Handicapped-Children.html or http://www.myyog.com/ please review...

    By Blogger ayurvijay, at 4:18 AM  

  • Hi, My Uncle also affected by Myopathy.This is confirmed by biopsy test. We like to do the Ayurvedic treatment. Please give your suggestion.

    By Blogger mgv, at 11:00 PM  

  • hi my daughter is suffering with spinal muscular atrophy type 1
    +. can this combination of ayurvedic medicine help my daughter at certain level.. plz guide!!!

    By Blogger ankita srivastava, at 3:03 AM  

  • My friend is suffering from Mitochondrial myopathy. Is there an ayurvedic treatment available for it ?

    By Blogger Anubha Gautam, at 9:45 AM  

  • My friend is suffering from Mitochondrial myopathy. Is there an ayurvedic treatment available for it ?

    By Blogger Anubha Gautam, at 9:46 AM  

  • My son is 8 yrs old suffering with Duchenne muscular dystrophy. He is not walking properly and fell down frequently. Kindly give your suggestions and treatment if any, thanking you sir.

    By Blogger Unknown, at 8:05 AM  

  • My brother is 44 years, suffering from Becker muscular dystropy, please suggest any treatment

    By Blogger Unknown, at 2:16 AM  

  • i am suffering from SMA since 8 years.now,i am unable to walk.i need some support to walk. most of the time i feel comfort in sitting or sleeping. let me know whether there is treatment at ur hospital. rajagopal.bulusu@gmail.com

    By Blogger Unknown, at 10:49 AM  

  • Hi I am Guru Prakash from Bangalore, My son is effectected with mitochondrial disease with complex I & Complex IV, he is unable to breath, he is on ventilator at hospital. so plz suggest me to save my child

    By Blogger Unknown, at 9:58 PM  

  • Respected Sir,
    Myself sujit kumar sharma, My son Aniket Sharma is 8 yrs old suffering with Duchenne muscular dystrophy. He is not walking properly and fell down frequently. Kindly give your suggestions and treatment if any, thanking you sir.
    Sujit_sharma10@rediffmail.com

    By Blogger sujit, at 4:38 AM  

  • Hi ankita

    My 1 month old son is suffering with small Type can you guide e me how to take care based on your experience. My mail is Grandhi.Pavan@gmail.com

    My phone number is 8008766599

    By Blogger Unknown, at 6:45 AM  

  • Can we reduce the growth of congenital muscle disease by drinking a glass of Goji Berry Juice? I have heard that people who eat goji berries or drink its nectar experience less skin and muscle problems.

    By Blogger Unknown, at 10:06 PM  

  • Hi there....
    My sister's 4 months old baby girl is confirmed with SMA TYPE 1 disease... Can anyone help me and my family in this sad situation, is there any ayurvedic treatment for this disease ? Or where can i get the best treatment for our baby? Please do help me... My email id is given pprasanth330@gmail.com

    By Blogger Unknown, at 1:04 PM  

  • A Patanjali ayurvedic health product is the best option for health. These products are having a wide range. For more information please visit our site:- online ayurvedic medicine

    By Blogger patanjaliayurved, at 11:25 PM  

  • Irrespective of receiving daily oral or future injectable depot therapies, these require health care visits for medication and monitoring of safety and response. If patients are treated early enough, before a lot of immune system damage has occurred, life expectancy is close to normal, as long as they remain on successful treatment. However, when patients stop therapy, virus rebounds to high levels in most patients, sometimes associated with severe illness because i have gone through this and even an increased risk of death. The aim of “cure”is ongoing but i still do believe my government made millions of ARV drugs instead of finding a cure. for ongoing therapy and monitoring. ARV alone cannot cure HIV as among the cells that are infected are very long-living CD4 memory cells and possibly other cells that act as long-term reservoirs. HIV can hide in these cells without being detected by the body’s immune system. Therefore even when ART completely blocks subsequent rounds of infection of cells, reservoirs that have been infected before therapy initiation persist and from these reservoirs HIV rebounds if therapy is stopped. “Cure” could either mean an eradication cure, which means to completely rid the body of reservoir virus or a functional HIV cure, where HIV may remain in reservoir cells but rebound to high levels is prevented after therapy interruption.Dr Itua Herbal Medicine makes me believes there is a hope for people suffering from,Parkinson's disease,Schizophrenia,Lung Cancer,Breast Cancer,psoriasis,Colo-Rectal Cancer,Blood Cancer,Prostate Cancer,siva.Fatal Familial Insomnia Factor V Leiden Mutation ,Epilepsy Dupuytren's disease,Desmoplastic small-round-cell tumor Diabetes ,Coeliac disease,Creutzfeldt–Jakob disease,Cerebral Amyloid Angiopathy, Ataxia,Arthritis,Amyotrophic Lateral Scoliosis,Fibromyalgia,Fluoroquinolone Toxicity
    Syndrome Fibrodysplasia Ossificans ProgresSclerosis,Alzheimer's disease,Adrenocortical carcinoma.Asthma,Allergic diseases.Hiv_ Aids,Herpe ,Copd,Glaucoma., Cataracts,Macular degeneration,Cardiovascular disease,Lung disease.Enlarged prostate,Osteoporosis.Alzheimer's disease,
    Dementia.(measles, tetanus, whooping cough, tuberculosis, polio and diphtheria),Chronic Diarrhea,
    Hpv,All Cancer Types,Diabetes,Hepatitis,I read about him online how he cure Tasha and Tara so i contacted him on drituaherbalcenter@gmail.com / . even talked on whatsapps +2348149277967 believe me it was easy i drank his herbal medicine for two weeks and i was cured just like that isn't Dr Itua a wonder man? Yes he is! I thank him so much so i will advise if you are suffering from one of those diseases Pls do contact him he's a nice man.

    By Blogger Unknown, at 10:00 PM  

  • Am Richard, I am here to testify about a great herbalist  man who cured my wife of breast cancer. His name is Dr Imoloa. My wife went through this pain for 3 years, i almost spent all i had, until i saw some testimonies online on how Dr. Imoloa cure them from their diseases, immediately i contacted him through. then he told me the necessary things to do before he will send  the herbal medicine. Wish he did through DHL courier service, And he instructed us on how to apply or drink the medicine for good two weeks. and to greatest surprise before the upper third week my wife was relief from all the pains, Believe me, that was how my wife was cured from breast cancer by this great man. He also have powerful herbal medicine to cure diseases like: Alzheimer's disease, parkinson's disease, vaginal cancer, epilepsy Anxiety Disorders, Autoimmune Disease, Back Pain, Back Sprain, Bipolar Disorder, Brain Tumor, Malignant, Bruxism, Bulimia, Cervical Disc Disease, Cardiovascular Disease, Neoplasms , chronic respiratory disease, mental and behavioral disorder, Cystic Fibrosis, Hypertension, Diabetes, Asthma, Autoimmune inflammatory media arthritis ed. chronic kidney disease, inflammatory joint disease, impotence, alcohol spectrum feta, dysthymic disorder, eczema, tuberculosis, chronic fatigue syndrome, constipation, inflammatory bowel disease, lupus disease, mouth ulcer, mouth cancer, body pain, fever, hepatitis ABC, syphilis, diarrhea, HIV / AIDS, Huntington's disease, back acne, chronic kidney failure, addison's disease, chronic pain, Crohn's pain, cystic fibrosis, fibromyalgia, inflammatory Bowel disease, fungal nail disease, Lyme disease, Celia disease, Lymphoma, Major depression, Malignant melanoma, Mania, Melorheostosis, Meniere's disease, Mucopolysaccharidosis, Multiple sclerosis, Muscular dystrophy, Rheumatoid arthritis. You can reach him Email Via drimolaherbalmademedicine@gmail.com / whatsapp +2347081986098    Website/ www.drimolaherbalmademedicine.wordpress.com

    By Blogger Richard William, at 7:48 PM  

Post a Comment

<< Home